N,N-dimethyl-1,2,4,5,6,7-hexahydrothiocino[5,4 -b]-indole-7-propanamine-3,3-dioxides and related thiocines
US4144349A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1977 |
| Grant date | Mar 13, 1979 |
| Priority date | — |
| Expiry date | Dec 23, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel compounds having the formula I: ##STR1## wherein R is hydrogen, lower alkyl, lower alkoxy or halogen; R' is amino lower alkyl wherein the amino group is unsubstituted or substituted by mono- or di(lower alkyl); and X is S or SO.sub.2 ; and the non-toxic, pharmaceutically acceptable salts thereof, which are useful as antidepressants. Intermediates having the formula IV, which are used in the preparation of the compounds having the formula I are also disclosed: ##STR2## wherein R is hydrogen, lower alkyl, lower alkoxy or halogen; and X is S or SO.sub.2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.