Novel agents and novel methods for treatment of climacteric disturbances

US4145416A · kind A · utility

Assignee

• Schering A.G. · DE

Inventors

• Ursula Lachnit-Fixson · Berlin, DE
• Friedmund Neumann · Berlin, DE

Key dates

• Filing date: Sep 27, 1977
• Grant date: Mar 20, 1979
• Expiry date: Sep 27, 1997

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/565
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Relief from climacteric disturbances is achieved by administration of first a combination of an estrogen of type 1 and an estrogen of type 2, approximately in a ratio of 2:1 to 1:8, daily over 10-12 days; then a combination of an estrogen of type 1 and an estrogen of type 2, approximately in a ratio of 2:1 to 1:8, and a progestogen, daily over 9-11 days; and thereafter an estrogen of type 2, or a placebo, daily over 6-8 days.