Patent · US Expired

Hydroxy acids

US4145437A · kind A · utility

3Cited by
0References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 25, 1977
Grant dateMar 20, 1979
Priority date
Expiry dateOct 25, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C59/285
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the invention are 2-(5.beta.-n-butyl-4.beta.-hydroxy-2-oxo-tetrahydrofuran-3.beta.-yl)-2.alp ha.-methyl-acetic acid and 3.alpha.-methyl-5.beta.-(1.beta.-hydroxy-n-pentyl)-2-oxo-tetrahydrofuran-4 .beta.-ylcarboxylic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.