Hydroxy acids
US4145437A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 25, 1977 |
| Grant date | Mar 20, 1979 |
| Priority date | — |
| Expiry date | Oct 25, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/285
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns novel racemic and optically active mono- and di-hydroxy alkanoic acids bearing phenyl and/or alkyl substituents, processes for their preparation, and pharmaceutical compositions for therapeutic use in the treatment of duodenal or gastric ulcers. Representative compounds of the invention are 2-(5.beta.-n-butyl-4.beta.-hydroxy-2-oxo-tetrahydrofuran-3.beta.-yl)-2.alp ha.-methyl-acetic acid and 3.alpha.-methyl-5.beta.-(1.beta.-hydroxy-n-pentyl)-2-oxo-tetrahydrofuran-4 .beta.-ylcarboxylic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.