Preparation of vincamine and related alkaloids
US4145552A · kind A · utility
3Cited by
2References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 5, 1977 |
| Grant date | Mar 20, 1979 |
| Priority date | — |
| Expiry date | Jul 5, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D461/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing vincamine and related alkaloids, comprising reacting a compound of formula: ##STR1## (wherein R is H or methoxy and X and Y are hydrogen or together represent a double bond between the carbon atoms to which they are bonded) with a carbanion-forming agent in a reaction medium; then introducing oxygen into the reaction medium until saturation point, a reducing agent compatible with oxygen being added to the reaction medium before the medium ceases absorbing oxygen; acidifying the mixture and extracting therefrom a mixture of compounds ##STR2##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.