1,2-Dihydronaphthalene derivatives and pharmaceutical composition
US4148897A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 20, 1977 |
| Grant date | Apr 10, 1979 |
| Priority date | — |
| Expiry date | Apr 20, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/192
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 1,2-dihydronaphthalene derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are hydrogen, nitro, amino, halogen, or hydroxyl which may be protected, and R.sup.3 is a piperazinyl or morpholino group which may be substituted by lower alkyl, aralkyl, carboxylic acid-derived acyl, lower alkoxycarbonyl-lower alkyl or cycloaminocarbonyl-lower alkyl, and its salts have excellent pharmacological activities such as vasodilator and cerebral blood flow increasing activities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.