Patent · US Expired

1,2-Dihydronaphthalene derivatives and pharmaceutical composition

US4148897A · kind A · utility

6Cited by
5References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 20, 1977
Grant dateApr 10, 1979
Priority date
Expiry dateApr 20, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/192
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel 1,2-dihydronaphthalene derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are hydrogen, nitro, amino, halogen, or hydroxyl which may be protected, and R.sup.3 is a piperazinyl or morpholino group which may be substituted by lower alkyl, aralkyl, carboxylic acid-derived acyl, lower alkoxycarbonyl-lower alkyl or cycloaminocarbonyl-lower alkyl, and its salts have excellent pharmacological activities such as vasodilator and cerebral blood flow increasing activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.