Indolyl cyanomethylphenethanolamines
US4148908A · kind A · utility
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5Claims
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Key dates
| Filing date | Sep 22, 1977 |
| Grant date | Apr 10, 1979 |
| Priority date | — |
| Expiry date | Sep 22, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-[1-hydroxy-2-[(1,1-dimethyl-2-phenylethyl)amino]ethyl]-benzene acetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.