Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions

US4151303A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Ernst-Christian Witte · Mannheim, DE
• Hans-Peter Wolff · Mannheim, DE
• Kurt Stach
• Wolfgang Schaumann · Heidelberg, DE
• Karlheinz Stegmeier · Heppenheim, DE

Key dates

• Filing date: Sep 1, 1976
• Grant date: Apr 24, 1979
• Expiry date: Sep 1, 1996

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P3/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel phenoxyalkylcarboxylic acid compounds of the formula ##STR1## wherein A is aryl, aryloxy, substituted aryl or substituted aryloxy, wherein the substituents are selected from lower alkyl, lower alkoxy, halogen and haloalkyl; PA1 B is a straight-chained or branched, saturated or unsaturated hydrocarbyl containing up to 5 carbon atoms; PA1 N is 1, 2 or 3 and PA1 R.sub.1, r.sub.2 and R.sub.3, which may be the same or different, are hydrogen or lower alkyl; PA1 And the pharmacologically compatible salts thereof; have been found to be outstandingly effective in depressing serum-lipid and triglycerides in the serum of mammals.