Patent · US Expired

Crystalline potassium salt of .beta.-nicotinamide adenine dinucleotide phosphoric acid and method for its preparation

US4151349A · kind A · utility

6Cited by

1References

1Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Heinrich Traeger · Meerbusch, DE
Herbert Brustmann · Tutzing, DE
Erich Haid · Tutzing, DE

Key dates

Filing date	Sep 23, 1977
Grant date	Apr 24, 1979
Priority date	—
Expiry date	Sep 23, 1997

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/207
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention provides a novel crystalline potassium salt of .beta.-nicotinamide adenine dinucleotide phosphoric acid (.beta.-NADP-K), having a primitively orthorhombic crystal system, which salt is more pure and more stable than the conventional amorphous form, and is advantageously not hygroscopic. The novel salt is produced by treating a dilute aqueous solution of the potassium salt of .beta.-nicotinamide adenine dinucleotide phosphoric acid with a hydrophilic water soluble organic solvent at a pH value of 2 to 5 until turbidity sets in, permitting crystallization and then separating the crystals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.