Patent · US Expired

Novel 17-spirosultines

US4154730A · kind A · utility

1Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 20, 1977
Grant dateMay 15, 1979
Priority date
Expiry dateOct 20, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J33/005
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel 17-spirosultines of steroids and the corresponding .gamma.-hydroxy acids of the formula ##STR1## wherein R.sub.1 is alkyl of 1 to 4 carbon atoms, A is hydrogen and B is hydrogen or hydroxyl of .beta.configuration or A and B together form a double bond, X and Y together form the group ##STR2## or X is --OH and Y is ##STR3## and M is selected from the group consisting of hydrogen, --NH.sub.4 and an alkali metal having a remarkable progestomimetic and antialdosteronic activity and a novel process for their preparation and novel intermediates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.