Preparation of dithiophosphoric acid diester-halides

US4154780A · kind A · utility

Assignees

• BAYER HEALTHCARE LLC · DE
• Mobay Chemical Corporation · US

Inventors

• Reimer Colln · Wuppertal, DE
• Hermann Arold · Wuppertal, DE
• Vidyanatha A. Prasad · Leawood, US

Key dates

• Filing date: Mar 31, 1977
• Grant date: May 15, 1979
• Expiry date: Mar 31, 1997

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B32B27/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of a dithiophosphoric acid diester-halide of the formula ##STR1## IN WHICH R.sup.1 is alkyl with 1 to 10 carbon atoms, aralkyl with 1 to 6 carbon atoms in the alkyl radical, or alkoxyalkyl or alkylthioalkyl with 1 to 5 carbon atoms in each alkyl radical, PA1 R.sup.2 is alkyl with 1 to 8 carbon atoms, and PA1 Hal is halogen, Which comprises reacting an S-alkyl or S-aralkyl ester of a dithiophosphoric acid dihalide of the formula ##STR2## WITH ABOUT A 5 TO 300% MOLAR EXCESS OF AN ALCOHOL OF THE FORMULA EQU R.sup.2 OH in the presence of about a 5 to 300% molar excess of a tertiary pyridine base or tertiary aralkyl-alkylamine at a temperature between about -10.degree. and +60.degree. C. Advantageously the tertiary base is pyridine, 2-, 3- or 4-methyl-pyridine, 4-ethyl-pyridine, 5-ethyl-2-methyl-pyridine, 2,4- or 2,6-dimethyl-pyridine, 2,4,6-trimethyl-pyridine, quinoline, isoquinoline, 2-, 4- or 6-methyl-quinoline, 6-chloro-2-methyl-quinoline, 2-chloro-4-methyl-quinoline, 8-chloro-2-methyl-quinoline or dimethylbenzylamine, the reaction is carried out at about 0.degree. to 30.degree. C., the alcohol is ethanol employed in about a 15 to 30% molar excess, abou…