Pharmaceutical compositions
US4156002A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 13, 1978 |
| Grant date | May 22, 1979 |
| Priority date | — |
| Expiry date | Feb 13, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns pharmaceutical compositions having analgesic, and in some cases, in addition anti-inflammatory properties, for use in the treatment of painful inflammatory joint disease, which compositions contain as active ingredient a new or old 1-alkyl (or cycloalkyl)-4-(N-alkanoyl)substituted-amino-tetrahydro-1,3,5-triazine-2,6- dione of the formula: ##STR1## or a base-addition salt thereof. Many of the compounds of formula I are previously known as herbicides, and a representative example of such a compound which has now been surprisingly found to have useful analgesic properties is 1-isopropyl-4-(N-acetyl)isopropylamino-tetrahydro-1,3,5-triazine-2,6-dione . However certain of the compounds of formula I and the base-addition salts thereof are novel, a representative example being 1-isopropyl-4[(N-acetyl)pent-3-ylamino]-tetrahydro-1,3,5-triazine-2,6-dion e, and are provided as a further feature of the invention, together with analogy processes for their manufacture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.