Derivatives of 1,2-benzisoxazoles
US4156005A · kind A · utility
20Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1978 |
| Grant date | May 22, 1979 |
| Priority date | — |
| Expiry date | Jun 21, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/565
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted 1,2-benzisoxazoles of the formula ##STR1## where: R.sup.1 and R.sup.3 =H or lower alkoxy; PA1 R.sup.2 =halo or .alpha.-branched lower alkyl; PA1 R.sup.4 =halo, halo lower alkyl, or lower alkylthio; provided, where R.sup.1 and R.sup.3 =H, PA1 R.sup.2 and R.sup.4 are other than simultaneously Cl or Br, which are active as antiinflammatory, antipyretic and analgesic agents, are derived from cyclodehydrating the corresponding salicylaldoximes with an isocyanate under extremely mild conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.