Theophylline antigens and antibodies
US4156081A · kind A · utility
12Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1977 |
| Grant date | May 22, 1979 |
| Priority date | — |
| Expiry date | Apr 15, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Theophylline derivatives are provided for preparing reagents for use in competitive protein binding assays and for use as reagents in competitive protein binding assays. Theophylline is substituted at the 3 position and conjugated to antigens for production of antibodies which specifically recognize theophylline as distinct from structurally similar analogs such as caffeine. Enzyme conjugates are provided which find use for measuring the amount of theophylline in a sample suspected of containing theophylline. A method is provided employing the reagents for the determination of theophylline.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.