Benzo(B)thiophenes
US4157399A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 5, 1977 |
| Grant date | Jun 5, 1979 |
| Priority date | — |
| Expiry date | Dec 5, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/66
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new derivatives of 2-phenyl -benzo(b)thiophene mono- or disubstituted on the nitrogen atom of formula ##STR1## in which X.sup.1 to X.sup.9 which are identical or different are hydrogen, alkyl having up to 3 carbon atoms, chlorine, bromine, methoxy or methylthio, R.sup.1 is hydrogen, alkyl having up to 8 carbon atoms, optionally chlorinated or methoxylated, phenyl optionally chlorinated or methoxylated, aralkyl having in all up to 9 carbon atoms, optionally chlorinated or methoxylated on the phenyl nucleus, R.sup.2 is hydrogen, phenyl, Or a radical of the formula ##STR2## in which A is two hydrogen atoms or one oxygen atom and PA1 R.sup.3 can assume the same meanings as given for R.sup.1, the meanings assumed by R.sup.1 and R.sup.3 being independent from one another, or R.sup.1 and R.sup.2 together form the radical of a Schiff base of formula EQU .dbd.CH--R.sup.4 (III) in which R.sup.4 is not hydrogen, but can otherwise assume the same meanings as R.sup.3, or the group ##STR3## forms the radical of a heterocyclic secondary amine. The invention also relates to the acid addition salts of the above compounds, notably those which are pharmaceutically com…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.