Fungicidally active antibiotic from Streptomyces tendae Ettlinger

US4158608A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ursula Dahn
• Hanspaul Hagenmaier
• Helmut Hohne
• Wilfried Konig · Pinneberg, DE
• Hans Scheinpflug · Leverkusen, DE
• Hans Zahner · Quakenbrück, DE

Key dates

• Filing date: Apr 7, 1977
• Grant date: Jun 19, 1979
• Expiry date: Apr 7, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/465
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The new antibiotic Nikkomycin is produced by culturing the strain Streptomyces tendae Ettlinger et al Tu 901 in a nutrient medium at a pH of about 5.5 to 8 under aerobic conditions and isolation by cation exchange from the culture filtrate, followed by elution. The antibiotic is believed to have the structural formula ##STR1## and is characterized by fungicidal activity.