Patent · US Expired

Nuclear substituted 2-hydroxyphenylmethanesulfamic acids

US4159279A · kind A · utility

35Cited by
2References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 23, 1977
Grant dateJun 26, 1979
Priority date—
Expiry dateNov 23, 1997

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P29/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Nuclear substituted 2-hydroxyphenylmethanesulfamic acids and their pharmaceutically acceptable salts wherein the phenyl nucleus is substituted with 2 to 4 nuclear substituents and which are useful saluretic-diuretics and anti-inflammatories are disclosed. The products may be prepared by reacting nuclear substituted salicylaldehydes with ammonium sulfamate to generate intermediate imines which are reduced to afford the compounds of this invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.