Therapeutic device for osmotically dosing at controlled rate
US4160020A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1977 |
| Grant date | Jul 3, 1979 |
| Priority date | — |
| Expiry date | Dec 27, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An osmotic device is disclosed for delivering an active agent. The device comprises a wall surrounding a compartment with a passageway through the wall for releasing the agent. The wall comprises a material permeable to an external fluid and substantially impermeable to agent and at least one additional material independently selected from materials that impart stability to the wall, enhance the permeability of the wall to fluids, or aid in forming the wall. The compartment contains an agent that exhibits an osmotic pressure gradient across the wall against an external fluid, or the agent is mixed with an osmotically effective compound that exhibits an osmotic pressure gradient against the fluid. Agent is released from the device by fluid being imbided through the wall into the compartment at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall, thereby producing a solution containing agent that is released through the passageway at a controlled rate over time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.