Process for the preparation of thieno(2,3-c)- and thieno(3,2-c)pyridines
US4161599A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 23, 1978 |
| Grant date | Jul 17, 1979 |
| Priority date | — |
| Expiry date | May 23, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a process for the preparation of derivatives having the formula: ##STR1## in which R is hydrogen or the carboxy group, comprising reacting a compound of the formula ##STR2## with nitrous acid, to give, respectively, the compounds of the formulae: ##STR3## and then removing the nitroso group from the compounds of the formulae (V) and (VI), respectively, either by reaction with an acid, to give the derivatives of the formulae (I) and (II), respectively, in which R is hydrogen, or by reaction with an alkali metal hydroxide and subsequent neutralization, to give the derivatives of the formulae (I) and (II), respectively, in which R is the carboxy group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.