Method for purification of HBs antigen
US4162192A · kind A · utility
15Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 1978 |
| Grant date | Jul 24, 1979 |
| Priority date | — |
| Expiry date | Sep 28, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An improved method for purification of HBs antigen comprising passing a partially purified HBs antigen prepared from blood plasma or serum through a column filled with an anion exchanger which may be equilibrated with a buffer solution having a specific ionic strength and pH level, and further passing the resulting effluent through a column filled with a cation exchanger which may be equilibrated with a buffer solution having a specific ionic strength and pH level. The HBs antigen obtained by the present invention is highly purified and is useful for preparing vaccine for preventing Viral Hepatitis Type B.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.