Patent · US Expired

Benzo[b,f]thiepin derivatives and process for producing the same

US4166127A · kind A · utility

3Cited by
1References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 16, 1978
Grant dateAug 28, 1979
Priority date
Expiry dateJan 16, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D337/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel benzo [b,f] thiepin derivatives possessing strong anti-flammatory action and presenting few adverse reactions, of the formula (I) ##STR1## wherein R represents a fluorine atom, or a trifluoromethyl or 1-5C lower alkoxy group, and R.sub.3 and R.sub.4 each represent a 1-4C lower alkyl group or R.sub.3 and R.sub.4 together with the adjacent nitrogen atom to which they are attached form a heterocyclic group. Pharmaceutical compositions comprising an anti-inflammatory effective amount of the compound according to formula (I) in the presence of an inert carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.