Patent · US Expired

Continuous cell culture system

US4166768A · kind A · utility

23Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 14, 1977
Grant dateSep 4, 1979
Priority date
Expiry dateNov 14, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12M27/02
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A cell culture system and apparatus is provided for the suspension culturing of mammalian cells in which fresh media can be added and spent medium filtered and withdrawn on a continuous or semi-continuous basis without cell disruption. The apparatus comprises a hollow flask assembly having a hollow shaft means journaled for rotation in a stationary sleeve sub-assembly and a filter unit suspended downwardly therefrom, said filter unit being in fluid communication with the top opening of the flask through the interior of said hollow shaft means and adapted for coaxial rotation with said shaft means.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.