Phlorethyl-.beta.-alanyl-secretine
US4167508A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 17, 1977 |
| Grant date | Sep 11, 1979 |
| Priority date | — |
| Expiry date | Jun 17, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A radioiodinated phloretyl-.beta.-alanyl-secretin, its salts and its protected derivatives. A process for the manufacture of a radioiodinated phloretyl-.beta.-alanyl-secretin and/or a salt thereof which process involves reacting phloretyl-.beta.-alanyl-secretin and/or a salt thereof with radioactive iodine. Phloretyl-.alpha.-alanyl-secretin, its salts and its protected derivatives. A method for the determination of secretin in a sample, which involves; mixing the sample with a known amount of a radioiodinated phloretyl-.beta.-alanyl-secretin and an antibody specific for secretin; measuring the degree of binding of the labelled radioiodinated phloretyl-.beta.-alanyl-secretin; and determining the amount of secretin present in the sample by comparing the degree of binding with a standard curve which has been obtained by adding known amounts of secretin to a defined mixture of the radioiodinated phloretyl-.beta.-alanyl-secretin and the antibody and determining the degree of binding for this known amount of secretin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.