8-Azapurin-6-one derivatives
US4167568A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 20, 1977 |
| Grant date | Sep 11, 1979 |
| Priority date | — |
| Expiry date | Oct 20, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
8-Azapurin-6-one derivatives of the formula: ##STR1## wherein R.sup.8 represents alkoxy of from 1 to 6 carbon atoms, and R.sup.9 represents cyano, or a group of the formula V, VI, VII, VIII or IX indicated below: ##STR2## wherein R.sup.10, R.sub.13 and R.sup.14 each represents cyano, or alkanoyl or alkoxycarbonyl of from 2 to 6 carbon atoms, R.sup.11 represents hydrogen, cyano, or alkanoyl or alkoxycarbonyl of from 2 to 6 carbon atoms, R.sup.12 represents hydrogen or, when R.sup.11 represents hydrogen, R.sup.12 represents alkyl of from 1 to 6 carbon atoms or alkoxycarbonyl of from 2 to 6 carbon atoms, or the pair of symbols R.sup.11 and R.sup.12 form together an alkylene chain of the formula --(C.sub.q H.sub.2q)-- wherein q is an integer from 3 to 6, R.sup.15 and R.sup.16 each represents hydrogen or alkyl of from 1 to 6 carbon atoms, and Y.sup.1 represents oxygen or sulphur, are new compounds possessing pharmacological properties, in particular properties of value in the treatment of respiratory disorders such as allergic bronchial asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.