Pyrimido[1,2-a ]benzimidazole derivatives
US4167569A · kind A · utility
4Cited by
4References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 23, 1977 |
| Grant date | Sep 11, 1979 |
| Priority date | — |
| Expiry date | Nov 23, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns 3,4-dihydropyrimido [1,2-a]benzimidazole derivatives bearing one or more substituents at positions 6, 7, 8 or 9; processes for their preparation and manufacture; and pharmaceutical compositions thereof. The compounds inhibit the aggregation of blood-platelets and may be used in vivo, in the treatment or prophylaxis of thrombosis or occlusive vascular disease, or in vitro, in helping to stabilize preparations of blood platelets. Representative compounds of the invention are 7- and 8- acetyl-3,4-dihydropyrimido[1,2-a]benzimidazol-2(1H)-one.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.