1-(Benzothien-2'-yl)-3-morpholino propanones and therapeutic compositions containing same
US4169892A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 3, 1978 |
| Grant date | Oct 2, 1979 |
| Priority date | — |
| Expiry date | Jan 3, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the formula ##STR1## wherein R.sub.1 and R.sub.2 are alkyls or alkenyls having one to 4 atoms or ##STR2## is pyrrolidino, piperidino, perhydroazepino or morpholino, and RX is a salt-forming moiety. The compounds are prepared by reacting 2-acetyl benzothiophene with ##STR3## The compounds possess a blood plaque aggregation inhibiting property and also possess spasmolytic, analgesic, anti-inflammatory and coronary, cerebral and peripheral vasodilatatory properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.