13-Halo and 13-deoxy C-076 compounds
US4171314A · kind A · utility
40Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1977 |
| Grant date | Oct 16, 1979 |
| Priority date | — |
| Expiry date | Dec 19, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/465
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Derivatives of the C-076 compounds are disclosed wherein the 13-position is unsubstituted or substituted by a halogen atom. The compounds are prepared by removing the glycosyl groups on the 13-position of the C-076 compounds isolated from the fermentation broth of Streptomyces avermitilis. This is followed by substitution of the 13-hydroxy group with a halogen, and subsequent removal of the halogen. The disclosed compounds are antiparasitic, anthelmintic, insecticidal and acaracidal agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.