Pyrimidine to pyrimidine transformation process
US4171429A · kind A · utility
12Cited by
0References
9Claims
0Family size
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Key dates
| Filing date | Mar 29, 1977 |
| Grant date | Oct 16, 1979 |
| Priority date | — |
| Expiry date | Mar 29, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is provided a novel process for pyrimidine to pyrimidine transformations by the displacement of the 1,2,3-portion of a pyrimidine by a 1,3-ambident nucleophile. The novel process requires that the 1 and 3 nitrogens of the pyrimidine moiety be substituted. The novel process makes available, inter alia, novel uracils, simple methods of radioisotopically labeling pyrimidine nuclei, a simple and inexpensive method of preparing the important antiviral and antileukemic material pseudoisocytidine and its new active analog 2'-deoxypseudoisocytidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.