Process for the production of substituted pyridine (C)

US4171444A · kind A · utility

Assignee

• Deutsche Gold- und Silber-Scheideanstalt Vormals Roessler

Inventors

• Helmut Beschke
• Heinz Friedrich · Hanau, DE
• Axel Kleeman · Hanau, DE

Key dates

• Filing date: Sep 6, 1977
• Grant date: Oct 16, 1979
• Expiry date: Sep 6, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Pyridines substituted in the 2- and 6-positions by an aromatic or heteroaromatic group are prepared by reacting an aromatic or heteroaromatic ketone having at least one reactive methylene group adjacent to the keto group with an aliphatic aldehyde and ammonia in the presence of a dehydrating and dehydrogenating catalyst at a temperature of about 250.degree. to 550.degree. C.