Patent · US Expired

Preparation of .alpha.-cyanocinnamaldehydes

US4172090A · kind A · utility

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2References
8Claims
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Assignee

Inventor

Key dates

Filing dateMay 12, 1977
Grant dateOct 23, 1979
Priority date
Expiry dateMay 12, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D317/60
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Benzaldehydes are reacted with cyanoacetaldehyde, for which reaction the cyanoacetaldehyde can be produced from isoxazole in a basic medium. The reaction gives .alpha.-cyanocinnamaldehydes, the hydrogenation of which gives the corresponding dihydrocinnamyl compounds, which can be converted to 2,4-diaminopyrimidines by reaction with guanidine, using various methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.