5-Phenyl-2,4-pentadien-1-amines and method for inhibiting prostaglandin dehydrogenase
US4173649A · kind A · utility
4Cited by
1References
3Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 27, 1978 |
| Grant date | Nov 6, 1979 |
| Priority date | — |
| Expiry date | Feb 27, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/99
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
5-Phenyl-2,4-pentadien-1-amines and salts thereof are provided having the structure ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, lower alkoxy, hydroxy, lower alkanoyloxy, nitro, cyano, amino, carboxy or lower alkoxycarbonyl, and R.sup.2 and R.sup.3 are the same or different and are hydrogen, lower alkyl, alkenyl-lower alkyl, aralkyl, and substituted lower alkyl. These compounds possess useful pharmceutical activites due to their ability to inhibit the prostaglandin-inactivating enzyme 15-.alpha.-hydroxyprostaglandin dehydrogenase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.