Sugar-coated solid dosage forms
US4176175A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 6, 1977 |
| Grant date | Nov 27, 1979 |
| Priority date | — |
| Expiry date | Jun 6, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2826
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The sugar-coated solid dosage forms have improved disintegrability even in a neutral medium after prolonged storage, with sugar-coating layers having excellent mechanical strengths. The coating layer that is in direct contact with the surface of the solid dosage form contains a water-insoluble hydroxypropyl cellulose with a relatively low content of hydroxypropoxy groups, say, from 4 to 16% by weight. The hydroxypropyl cellulose is used by being suspended in the coating syrup or mixed in the dusting powder for purposes of subcoating. It is also possible to use the hydroxypropyl cellulose in the form of suspension to form a smoothing coat.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.