Patent · US Expired

Etherified triazolobenzodiazepine derivatives

US4178378A · kind A · utility

0Cited by
2References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 15, 1977
Grant dateDec 11, 1979
Priority date
Expiry dateSep 15, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D317/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Etherified diazepine derivatives of the formula ##STR1## in which R.sub.1 represents hydrogen or alkyl having up to 3 carbon atoms, R.sub.2 and R.sub.3 independently of one another each represent hydrogen or alkyl having up to 7 carbon atoms, or represent the partial formula R.sub.4 --(OCH.sub.2 --CH.sub.2).sub.m, in which R.sub.4 represents hydrogen or alkyl having up to 7 carbon atoms and m represents the number 1 to 3, A.sub.1 represents alkylidene or alkylene having up to 3 carbon atoms, A.sub.2, depending on the meaning of n, represents alkylene or alkanetriyl having up to 5 carbon atoms, no carbon atom in the radical A.sub.2 being bonded to more than one oxygen atom, n represents the number 0 or 1, Ph represents substituted or unsubstituted 1,2-phenylene and Ar represents an aromatic radical, and their addition salts are manufactured according to methods known per se. They are useful in the treatment of states of epilepsy, stress and agitation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.