Novel tetrahydrocannabinol type compounds

US4179517A · kind A · utility

Assignee

• YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

• Raphael Mechoulam · Jerusalem, IL
• Naphtali Lander · Nes Ziona, IL
• Shabtay Dikstein · Jerusalem, IL
• Benyamin Shalita · Jerusalem, IL

Key dates

• Filing date: Dec 28, 1976
• Grant date: Dec 18, 1979
• Expiry date: Dec 28, 1996

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A pharmaceutical composition of matter substantially devoid of "cannabis-e" CNS activity containing as active ingredient a compound of the formula ##STR1## wherein A-----B designates a 1(2) or a 6(1) double bond and wherein R' designates --H or --CO--R where R is lower alkyl, and R" designates alkyl and novel compounds of the 3S,4S configuration of the formula ##STR2## wherein A----B designates a 1(2) or a 6(1) double bond, R' designates hydrogen or --CO--R where --R is lower alkyl, and R" designates alkyl of at least 6 carbon atoms.