Acyl-substituted phenyl esters of prostacyclin-type compounds
US4180657A · kind A · utility
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63Claims
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Inventor
Key dates
| Filing date | Aug 14, 1978 |
| Grant date | Dec 25, 1979 |
| Priority date | — |
| Expiry date | Aug 14, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C405/0083
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Acyl-substituted phenyl esters of prostacyclin-type compounds, for example the 4-acetylphenyl ester of prostacyclin (PGI.sub.2) illustrated by the formula ##STR1## and including esters of the isomeric 6-hydroxy-PGI.sub.1 and 6-keto-PGF.sub.1 .alpha. compounds, said esters having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.