Patent · US Expired

3-Amino-4-phenyl-1H-pyrazolo[3,4-b]pyridines and salts thereof

US4182887A · kind A · utility

4Cited by

2References

5Claims

0Family size

Assignee

Boehringer Ingelheim GmbH · DE

Inventors

Josef Roch · Biberach, DE
Erich Muller · Zell am Harmersbach, DE
Berthold Narr · Biberach, DE
Josef Nickl
Walter Haarmann

Key dates

Filing date	Sep 19, 1977
Grant date	Jan 8, 1980
Priority date	—
Expiry date	Sep 19, 1997

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D213/85
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1 is mono- or di-substituted amino, where the substituents are selected from the group consisting of alkyl of 1 to 6 carbon atoms, cyclohexyl, allyl and benzyl; unsubstituted, mono-substituted or di-substituted pyrrolidino, piperidino, hexamethyleneimino, morpholino, piperazino, thiomorpholino, 1-oxido-thiomorpholino or 1,1-dioxido-thiomorpholino, where the substituents are selected from the group consisting of methyl, hydroxymethyl, hydroxyl, phenyl and benzyl; 1,2,5,6-tetrahydropyridino; 1,2,3,4-tetrahydroisoquinolino; indolino; or 3,6-ethylene-hexamethyleneimino; PA1 R.sub.2 is hydrogen, methyl or benzyl; and PA1 R.sub.3 is hydrogen, halogen, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antiphlogistics and antithrombotics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.