Continuous cell culture system
US4184916A · kind A · utility
34Cited by
12References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 26, 1978 |
| Grant date | Jan 22, 1980 |
| Priority date | — |
| Expiry date | Jun 26, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M29/04
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A cell culture system and apparatus is provided for the suspension culturing of mammalian cells in which fresh media can be added and spent medium filtered and withdrawn on a continuous or semi-continuous basis without cell disruption. The apparatus comprises a hollow flask assembly having a hollow shaft means journaled for rotation in a stationary sleeve sub-assembly and a filter unit suspended downwardly therefrom, said filter unit being in fluid communication with the top opening of the flask through the interior of said hollow shaft means and adapted for coaxial rotation with said shaft means.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.