4-Phenyl-8-amino-tetrahydroisoquinolines and antidepressant use

US4185105A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Karl-Heinz Schmitt · Benoni, ZA
• Irmgard Hoffmann · Bad Soden am Taunus, DE
• Ulrich Schacht · Hofheim, DE

Key dates

• Filing date: May 30, 1978
• Grant date: Jan 22, 1980
• Expiry date: May 30, 1998

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

4-Phenyl-8-amino-tetrahydroisoquinolines of the formula ##STR1## in which R.sub.1 stands for bromine and R.sub.2 stands for hydrogen or both R.sub.1 and R.sub.2 represent chlorine, and their salts with physiologically tolerated acids, pharmaceutical preparations prepared therefrom, process for the manufacture of these preparations and their use for the treatment of depressive conditions.