Certain benzofuryl or benzothienyl-2-glyoxylic acid compounds
US4185110A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 9, 1978 |
| Grant date | Jan 22, 1980 |
| Priority date | — |
| Expiry date | Feb 9, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/78
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel benzoheterocyclylglyoxylic acid derivatives of the formula ##STR1## in which Z is free, etherified or acylated hydroxyl, X is thio or oxy, R is free or etherified hydroxyl, R.sub.1 is lower alkyl, cycloalkyl, hydroxyl, lower alkoxy, substituted or unsubstituted phenoxy, substituted or unsubstituted amino, acyl, carboxyl, halogen, nitro or, if Z is acylated hydroxyl and/or X is oxy, hydrogen, R.sub.2 is hydrogen, lower alkyl, hydroxyl or halogen and R.sub.3 and R.sub.4 are each hydrogen or lower alkyl, or in which two adjacent radicals R.sub.1, R.sub.2, R.sub.3 and R.sub.4 together form lower alkylene having 3 to 5 chain carbon atoms or 1,4-butadienylene and the other two radicals are each hydrogen, and their pharmaceutically acceptable salts are useful as anti-allergic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.