Cyclopentan-1-amines

US4188403A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Dieter Orth · Darmstadt, DE
• Hans-Eckart Radunz · Darmstadt, DE
• Manfred Baumgarth
• Jurgen Maisenbacher · Darmstadt, DE
• Reinhard Lissner · Amorbach, DE

Key dates

• Filing date: Dec 21, 1977
• Grant date: Feb 12, 1980
• Expiry date: Dec 21, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/74
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the Formula ##STR1## and the physiologically acceptable salts thereof, wherein R.sup.1 and R.sub.2 each is hydrogen or benzyl; R.sup.3 is alkyl of 5-10 C-atoms or 2-hydroxyalkyl of 5-10 C-atoms; R.sup.4 is hydrogen, methyl or ethyl; R.sup.5 is alkyl of 5-10 C-atoms or --C.sub.n H.sub.2n COOR.sup.6 ; R.sup.6 is hydrogen or alkyl of 1-4 C-atoms; and n is 0, 4, 5 or 6 are effective for inhibiting adhesion and/or agglomeration of thrombocytes.