Preparation of therapeutic compounds
US4188491A · kind A · utility
6Cited by
8References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1978 |
| Grant date | Feb 12, 1980 |
| Priority date | — |
| Expiry date | Mar 24, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for preparing arylpropionic acids of formula Ar--CH(CH.sub.3)--COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar--C(OH)(CH.sub.3)--COOH or its amide, and converting the acid or amide to the product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.