Patent · US Expired

Esters of cromoglycates

US4189571A · kind A · utility

29Cited by
2References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 7, 1978
Grant dateFeb 19, 1980
Priority date
Expiry dateFeb 7, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There are described compounds of formula I, ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are the same or different and each represent hydrogen, halogen, hydroxy, alkyl C 1 to 6, alkoxy C 1 to 6, hydroxy-alkoxy C 1 to 6, or alkoxy C 1 to 6-alkoxy C 1 to 6, PA1 X is a straight or branched C 2 to 10 hydrocarbon chain which may be substituted by an --OH group, PA1 Q is a group --CHR--Z PA1 R is hydrogen, alkyl C 1 to 8, phenyl, or alkoxy (C 1 to 8)-carbonyl, PA1 Z is a group --O--CO--Ra, --CO--ORa or --CONRbRc, PA1 Ra is cyclohexyl or cyclopentyl; straight or branched alkyl C 1 to 12, which is optionally substituted by cyclohexyl or cyclopentyl; alkenyl C 2 to 6, which is optionally substituted by phenyl; or, when Z is --CO--ORa, hydrogen, and PA1 Rb and Rc, which are the same or different, are each alkyl C 1 to 12. There are also described processes for making the compounds, and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.