Polypeptides related to somatostatin
US4190575A · kind A · utility
9Cited by
0References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 27, 1977 |
| Grant date | Feb 26, 1980 |
| Priority date | — |
| Expiry date | Dec 27, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## wherein: X is H, Ala-Gly, Gly-Gly-Gly, Ala-D-Ala, acetyl, or benzoyl; PA1 X.sub.1 is Arg or His; PA1 X.sub.2 is Glu or Asp; PA1 X.sub.3 is Trp or D-Trp; or 6-F-D-Trp; and PA1 X.sub.4 is Cys- or D-Cys; or a non-toxic pharmaceutically acceptable acid addition salt thereof; inhibit the secretion of growth hormone and glucagon without materially affecting the secretion of insulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.