Process for splitting the L-(-)-.alpha.-phenylethylamine salt of D-(-)-.alpha.-azidophenylacetic acid

US4190592A · kind A · utility

Assignee

• Dynamit Nobel GmbH · DE

Inventors

• Gunter Bison · Troisdorf, DE
• Reiner Elfgen · Troisdorf, DE
• Walter Heinzelmann · Odenthal, DE
• Josef Winterscheid · Sankt Augustin, DE
• Wolfgang Wolfes · Niederkassel, DE

Key dates

• Filing date: Sep 26, 1975
• Grant date: Feb 26, 1980
• Expiry date: Sep 26, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C247/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for splitting the L-(-)-.alpha.-phenylethylamine salt of D-(-)-.alpha.-azidophenylacetic acid which comprises the steps of mixing the salt with a liquid diluent and an acidic cation exchange material, effecting agitation of the resulting admixture and therefore isolating a highly purified D-(-)-.alpha.-azidophenylacetic acid. This acid product is characterized by an amine content of less than 0.2% by weight.