Polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract
US4190716A · kind A · utility
15Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 20, 1978 |
| Grant date | Feb 26, 1980 |
| Priority date | — |
| Expiry date | Dec 20, 1998 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S260/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A generic polymeric agent for releasing 5-aminosalicylic acid or its salts is disclosed which comprises a nonabsorbable pharmacologically acceptable organic polymer backbone containing aromatic rings to which are covalently bonded via azo bonds a plurality of salicylic acid or salicylate salt groups. The azo bonds attach to the salicylates' 5-position carbon. The polymers undergo bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid and/or its salts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.