Anti-hypertensive peptide analogs
US4191753A · kind A · utility
5Cited by
0References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 6, 1978 |
| Grant date | Mar 4, 1980 |
| Priority date | — |
| Expiry date | Nov 6, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel peptides having the sequence EQU <Glu-Trp-A.sub.3 -Arg-A.sub.5 -Gln-Ile-A.sub.8 -A.sub.9 wherein A.sub.3, A.sub.5, A.sub.8 and A.sub.9 are either L-proline or L-3,4-dehydroproline, are disclosed. These peptides are potent inhibitors of angiotensin converting enzyme and are useful as antihypertensive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.