Chemical compounds
US4193917A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1976 |
| Grant date | Mar 18, 1980 |
| Priority date | — |
| Expiry date | Aug 12, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D205/095
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel semisynthetic .beta.-lactam intermediates of use in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds are provided. The novel compounds are prepared from .beta.-lactams obtained by cleavage of the 1,2-sulphur-carbon bond of a penicillin 1-oxide (with subsequent internal or external trapping of the sulphur atom to leave a residual substituent as the .beta.-lactam nitrogen) by removal of the said residual substituent by an oxidative cleavage reaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.