Patent · US Expired

New pyrrole derivatives, process for their preparation and therapeutic applications thereof

US4194003A · kind A · utility

9Cited by
5References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 26, 1978
Grant dateMar 18, 1980
Priority date
Expiry dateSep 26, 1998

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P19/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to a compound selected from the compounds of the formula: ##STR1## in which: R.sup.1 is selected from hydrogen and C.sub.1-4 alkyl, PA1 R is selected from C.sub.1-6 alkyl, benzyl and phenyl, PA1 Ar is selected from phenyl, phenyl monosubstituted with a group selected from C.sub.1-4 alkyl, C.sub.1-4 alkoxy and halogen, phenyl polysubstituted with groups selected from C.sub.1-4 alkyl, C.sub.1-4 alkoxy and halogen, naphthyl, naphthyl monosubstituted with a group selected from C.sub.1-4 alkyl, C.sub.1-4 alkoxy and halogen, naphthyl polysubstituted with groups selected from C.sub.1-4 alkyl, C.sub.1-4 alkoxy and halogen, thienyl, furyl and pyrrolyl and > Z represents a carbonyl group, a group of the formula >C.dbd.NOH or an alcoholic group >CHOH and the salts of acids of formula (I) with physiologically acceptable bases. Said compounds are useful for the treatment of hyperuricemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.