Substituted benzenesulphonic acid esters, processes for their preparation and their use as medicaments

US4194004A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ekkehard Niemers · Wuppertal, DE
• Hartmund Wollweber · Wuppertal, DE
• Heinrich Kolling · Haan, DE
• Herbert Thomas

Key dates

• Filing date: Nov 2, 1977
• Grant date: Mar 18, 1980
• Expiry date: Nov 2, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C309/76
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel substituted benzenesulphonic acid esters, particularly useful as anthelmintics are provided. The novel compounds are those of the general formula ##STR1## in which R represents hydrogen, optionally substituted alkyl, cyano, alkoxy, halogen, trifluoromethyl, amino, acylamino or nitro, PA1 X represents SO.sub.3 and PA1 R.sup.1 and R.sup.2 are different from one another and individually represent one of the radicals ##STR2## wherein Y represents S and PA1 R.sub.3 represents hydrogen, optionally substituted alkyl or alkoxy, and salts thereof. Also included in the invention are methods for preparing the novel compounds, compositions containing them and methods for the use of the compounds and compositions.