Patent · US Expired

2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof

US4196291A · kind A · utility

6Cited by

4References

15Claims

0Family size

Assignee

MERCK PATENT GESELLSCHAFT MIT BESHRANK TER HAFTUNG · DE

Inventors

Jurgen Seubert · Darmstadt, DE
Herbert Thomas
Peter Andrews · Wuppertal, DE

Key dates

Filing date	Dec 18, 1978
Grant date	Apr 1, 1980
Priority date	—
Expiry date	Dec 18, 1998

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D217/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof. This is a division, or application Ser. No. 742,133, filed on Nov. 15, 1976, which in turn is a divisional of Ser. No. 533,467, filed on Dec. 16, 1974, now U.S. Pat. No. 4,001,411.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.