Substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols, their synthesis, their use and their compositions

US4198424A · kind A · utility

Assignee

• Byk Gulden Lomberg Chemische Fabrik GmbH · DE

Inventors

• Klaus Eistetter · Konstanz, DE
• Hans-Peter Kley · Allensbach, DE

Key dates

• Filing date: Nov 30, 1978
• Grant date: Apr 15, 1980
• Expiry date: Nov 30, 1998

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/22
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Selected substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols and their pharmacologically-acceptable acid-addition salts are useful as analgesics in human and veterinary medicine. Such compounds are prepared by reducing corresponding substituted 1-phenyl-2-pyrrolidin-2-yl ethanones and are formulated into medicinal compositions suitable for administration.